I wanted to share the project I actually do, this is the indominus rex from jurassic world, from Truong : https://gumroad.com/l/irexrig
I've actually model the anatomty from a bird / human / quadruped reference :
and re-rig and move full build pose to something more confortable for the simulation, then retarget this animation to start the muscle rig :
pass : irex
I've also model the fat before starting the muscle rig because I wanted to be sure to have no issue during the full process... This time I will try to simulate the muscle and the fat pass together so I've decide to split my fat layer on different part (head,upperBody, leg and tail).