It's possible that it's crashing due to running out of memory, but that's a bit surprising. Your OS should keep giving out virtual memory even when you run out of RAM. It should just make everything really slow. Viewing your memory usage up to the moment of the crash might help figure out of that's the problem.
You might want to try disabling all but one tissues. If that still crashes, then something strange is happening. Otherwise, keep re-enabling more of the tissues until it crashes again. If nothing else, this will help narrow down what's going wrong.
If you can send us full bug report and a scene that reliably crashes, I'd love to have a look at it and fix the plugin so it doesn't crash. At the very least, it should print an error message instead of crashing Maya.